Histiocytic Disorders

3 Types: (based on the types of histiocyte cells)

Dendritic cell disorder
  • most common disease in the groups is Langerhans Cell Histiocytosis (LCH)
  •  includes
    • Juvenile Xanthogranuloma (JXG)
    • Erdheim-Chester disease (ECD)

Macrophage cell disorder
  • includes
    • Hemophagocytic Lymphohistiocytosis (HLH)
    • Rosai-Dorfman disease (RD)

Malignant Histiocytosis
  • includes certain kinds of leukemia and malignant tumors

The guidelines for diagnosis, treatment, and follow-up have been created by the Histiocyte Society.

Resource:  www.histio.org